ZEMDAP® – M Tablet

Description

Composition (Each Film-Coated Tablet Contains):

• Dapagliflozin – 10 mg

• Metformin Hydrochloride – 500 mg

Category: Diabetes Care / Oral Antidiabetic Combination
Form: Oral Tablet
Pack Size: 10×10 Blister / Alu-Alu

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Product Description:

ZEMDAP® – M is a fixed-dose oral antidiabetic combination of Dapagliflozin, a selective SGLT2 inhibitor, and Metformin, a first-line insulin sensitizer. Together, they offer powerful and complementary blood glucose control, ideal for patients with type 2 diabetes mellitus (T2DM) who are inadequately managed with diet, exercise, or monotherapy. This combination not only lowers blood sugar but also supports weight loss, blood pressure reduction, and cardiovascular-renal protection.

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Key Benefits:

• Dual mechanism to improve fasting and postprandial glucose levels

• Aids weight reduction and improves insulin sensitivity

• Supports cardiovascular and renal protection in diabetic patients

• Lowers risk of hypoglycemia when used alone

• Effective and convenient once-daily dosing

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How it works:

• Dapagliflozin inhibits the SGLT2 transporter in the kidneys, reducing glucose reabsorption and increasing urinary glucose excretion.

• Metformin decreases hepatic glucose production, improves insulin sensitivity, and enhances peripheral glucose uptake.

Together, they work synergistically to achieve sustained glycemic control and reduce long-term diabetic complications.

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How to use:

• Take one tablet daily, preferably with the first main meal of the day, or as directed by your doctor.

• Swallow whole with a glass of water — do not crush or chew.

• Maintain adequate fluid intake throughout therapy.

• Regular blood sugar and renal function monitoring are recommended.

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Safety Advice:

• Low risk of hypoglycemia unless used with sulfonylureas or insulin.

• May cause mild gastrointestinal upset initially — taking with food helps reduce this.

• Stay well hydrated to avoid urinary or genital infections.

• Monitor kidney function before and during long-term therapy.

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Precautions:

• Not recommended in patients with type 1 diabetes or diabetic ketoacidosis (DKA).

• Use cautiously in patients with renal impairment, recurrent UTIs, or lactic acidosis risk factors.

• Avoid during pregnancy or breastfeeding unless clearly advised by your physician.

• Inform your doctor if you’re taking RAAS inhibitors, insulin, or diuretics.

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Storage:

Store in a cool, dry place away from sunlight and moisture.
Keep out of reach of children.