ZEMDAP® – V Tablet

Description

Composition (Each Film-Coated Tablet Contains):

• Dapagliflozin – 10 mg

• Vildagliptin – 100 mg

Category: Diabetes Care / Dual Oral Antidiabetics
Form: Oral Tablet
Pack Size: 10×10 Blister / Alu-Alu

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Product Description:

ZEMDAP® — V is a fixed-dose combination of Dapagliflozin, a selective SGLT2 inhibitor, and Vildagliptin, a potent DPP-4 inhibitor, formulated to offer synergistic glycemic control in patients with type 2 diabetes mellitus (T2DM). This dual-action therapy targets both fasting and post-meal glucose levels without causing weight gain or significant hypoglycemia. It is ideal for patients not adequately managed with monotherapy or lifestyle changes.

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Key Benefits:

• Controls both fasting and postprandial blood sugar

• Promotes urinary glucose excretion and enhances insulin release

• Does not cause weight gain or hypoglycemia when used alone

• Convenient once-daily oral dose

• Suitable for long-term diabetes care with cardiovascular-metabolic benefit

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How it works:

• Dapagliflozin blocks the SGLT2 transporter in renal tubules, reducing glucose reabsorption and increasing urinary glucose excretion.

• Vildagliptin inhibits the DPP-4 enzyme, increasing incretin levels (GLP-1 & GIP), which stimulate insulin release and suppress glucagon secretion in a glucose-dependent manner.

Together, they offer complementary mechanisms that reduce glucose levels throughout the day.

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How to use:

• Take one tablet once daily, preferably in the morning, with or without food, or as directed by your physician.

• Swallow whole with water — do not crush or chew.

• Ensure adequate fluid intake during therapy.

• Regularly monitor blood glucose and kidney function.

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Safety Advice:

• Generally well tolerated with a low risk of hypoglycemia.

• May cause mild urinary or genital infections — maintain proper hygiene and hydration.

• Routine monitoring of renal and liver function is recommended.

• Avoid alcohol to reduce the risk of lactic acidosis or dehydration.

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Precautions:

• Not for use in type 1 diabetes or diabetic ketoacidosis (DKA).

• Caution in patients with renal impairment, liver dysfunction, or history of pancreatitis.

• Not recommended during pregnancy or breastfeeding.

• Inform your physician of all other medications, including insulin or sulfonylureas.

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Storage:

Store in a cool, dry place away from direct sunlight.
Keep out of reach of children.