Description
Composition (Each Film-Coated Tablet Contains):
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Sitagliptin Phosphate – Equivalent to Sitagliptin 50 mg
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Metformin Hydrochloride (Sustained Release) – 500 mg
Category: Diabetes Care / DPP-4 Inhibitor + Biguanide Combination
Form: Oral Tablet
Pack Size: 10×10 Alu-Alu or Blister Pack
Product Description:
SUGAWELL® – M is a fixed-dose combination of Sitagliptin, a DPP-4 inhibitor, and Metformin, an insulin sensitizer, indicated for adults with type 2 diabetes mellitus (T2DM) who are inadequately controlled by diet, exercise, or monotherapy. This dual mechanism supports comprehensive glycemic control, without weight gain or significant risk of hypoglycemia.
Key Benefits:
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Effectively lowers fasting and postprandial blood glucose
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Improves insulin sensitivity and reduces hepatic glucose output
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Low risk of hypoglycemia when used alone
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Weight-neutral and well tolerated in long-term use
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Suitable for early-stage or combination-based diabetes therapy
How it works:
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Metformin works by decreasing glucose production in the liver and increasing insulin sensitivity in muscle tissue.
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Sitagliptin inhibits DPP-4, prolonging incretin activity (GLP-1 & GIP), which boosts insulin release and reduces glucagon secretion in a glucose-dependent manner.
Together, they offer synergistic glycemic control while minimizing side effects.
How to use:
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Take one tablet once daily, preferably with food, or as prescribed by your doctor
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Swallow whole with a full glass of water — do not crush or chew
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Maintain adequate hydration and monitor blood glucose regularly
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Follow lifestyle recommendations alongside therapy for best results
Safety Advice:
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May cause mild gastrointestinal discomfort initially — usually subsides over time
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Risk of lactic acidosis is rare but serious — avoid excessive alcohol and dehydration
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Low risk of hypoglycemia unless used with insulin or sulfonylureas
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Regular monitoring of blood sugar, kidney function, and HbA1c is advised
Precautions:
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Not for use in type 1 diabetes or diabetic ketoacidosis (DKA)
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Use with caution in patients with renal or hepatic impairment
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Avoid during pregnancy and breastfeeding unless clearly indicated
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Inform your doctor of all ongoing medications, especially other antidiabetics or cardiovascular drugs
Storage:
Store in a cool, dry place, away from direct sunlight.
Keep out of reach of children.
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