SUGATAB® – M3/850 Tablet

Description

Composition (Each Film-Coated Tablet Contains):

• Glimepiride – 3 mg

• Metformin Hydrochloride – 850 mg

Category: Diabetes Care / Sulfonylurea + Biguanide Combination
Form: Oral Tablet
Pack Size: 10×10 Alu-Alu or Blister Pack

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Product Description:

SUGATAB® – M3/850 is a fixed-dose combination of Glimepiride, a sulfonylurea that stimulates insulin secretion, and Metformin, a first-line biguanide that enhances insulin sensitivity. It is formulated for patients with type 2 diabetes mellitus (T2DM) who require stronger glycemic control and are not adequately managed on lower-dose combinations or monotherapy. This higher-strength formulation supports HbA1c reduction, post-meal glucose control, and long-term diabetes management.

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Key Benefits:

• Dual mechanism targets insulin resistance and secretion

• High-strength dose for patients with moderate to advanced T2DM

• Controls both fasting and postprandial blood sugar levels

• Helps reduce HbA1c effectively with once-daily dosing

• Cost-effective treatment with broad therapeutic reach

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How it works:

• Glimepiride stimulates insulin release from functional pancreatic beta cells in a glucose-dependent manner

• Metformin reduces hepatic glucose production and improves peripheral insulin sensitivity, enhancing glucose uptake by muscles and fat

Together, they provide broad-spectrum glucose control throughout the day.

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How to use:

• Take one tablet once daily, preferably with breakfast or the first major meal

• Swallow whole with water — do not split or chew

• Dose should be individualized based on patient response and physician’s recommendation

• Maintain a healthy lifestyle, diet, and exercise plan alongside medication

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Safety Advice:

• May cause hypoglycemia if meals are skipped — always eat after taking the tablet

• Gastrointestinal discomfort (due to Metformin) may occur initially

• Avoid alcohol to reduce risk of lactic acidosis and hypoglycemia

• Regular monitoring of blood glucose, kidney function, and HbA1c is recommended

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Precautions:

• Not recommended in type 1 diabetes, diabetic ketoacidosis, or severe renal/hepatic impairment

• Caution in elderly, debilitated, or malnourished patients

• Not to be used during pregnancy or breastfeeding unless medically advised

• Inform your doctor about all other antidiabetic or cardiovascular medications

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Storage:

Store below 25°C in a dry place.
Keep away from direct sunlight and moisture.
Keep out of reach of children.