AUGJET®-CV Injection

Description

Composition (Per Vial):

• Amoxicillin Sodium – 1000 mg

• Potassium Clavulanate – 200 mg
  Form: Sterile powder for reconstitution
  Route of Administration: Intravenous (IV) only
  Pack Size: 1 vial (with optional sterile water for injection)
  Category: β-lactam + β-lactamase inhibitor | Antibiotic Injection

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Product Description:

AUGJET®-CV combines Amoxicillin, a broad-spectrum penicillin-type antibiotic, with Clavulanic acid, a β-lactamase inhibitor, to combat resistant bacterial strains.
This potent combination offers enhanced protection against β-lactamase-producing organisms, making it highly effective in treating moderate to severe infections across respiratory, urinary, gastrointestinal, skin, and soft tissues.

Ideal for hospitalized patients and post-operative prophylaxis, AUGJET®-CV ensures broad antibacterial coverage, including Gram-positive, Gram-negative, and anaerobic pathogens.

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Key Benefits:

• Effective against β-lactamase-producing resistant organisms

• Suitable for severe infections:

  • Respiratory tract (pneumonia, bronchitis)

  • Urinary tract

  • Intra-abdominal and pelvic infections

  • Skin and soft tissue infections

• Supports surgical prophylaxis and hospital-acquired infections

• Offers a wider antimicrobial spectrum than amoxicillin alone

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How It Works:

• Amoxicillin inhibits bacterial cell wall synthesis, leading to cell lysis.

• Clavulanic acid irreversibly binds to β-lactamase enzymes produced by resistant bacteria, protecting amoxicillin from degradation and restoring its efficacy.

This synergy allows the formulation to kill a wider range of pathogens, even those resistant to amoxicillin alone.

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How to Use:

• Reconstitute with sterile water for injection

• Administer by slow IV injection or infusion over 30–40 minutes

• Dosage and frequency should be guided by a physician, based on infection severity, site, and patient condition

• Not for intramuscular use

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Safety Advice:

• Perform sensitivity testing before use when possible

• Monitor renal function, especially in elderly or renal-impaired patients

• Ensure adequate hydration during therapy

• Use cautiously in patients with penicillin allergies

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Precautions:

• Contraindicated in patients with a history of hypersensitivity to penicillins or β-lactam antibiotics

• May cause mild GI upset, rash, or rare hypersensitivity reactions

• Prolonged use may lead to secondary infections such as C. difficile-associated diarrhea

• Store below 25°C; protect from moisture and light

• Use immediately after reconstitution – single-use vial