CEFOLITE®-TZ 1.125 Injection

Description

Composition (per vial):

• Ceftriaxone Sodium – 1 g

• Tazobactam Sodium – 125 mg

Form: Sterile powder for reconstitution
Route: Intravenous (IV) / Intramuscular (IM) use
Pack Size: Single-use vial with sterile water for injection (optional)
Category: Prescription Injectable | Beta-Lactam + Beta-Lactamase Inhibitor

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Product Description:

CEFOLITE®-TZ 1.125 Injection is a powerful combination of Ceftriaxone, a third-generation cephalosporin antibiotic, and Tazobactam, a beta-lactamase inhibitor. This dual-action formula is effective against a wide range of resistant gram-positive and gram-negative bacteria, including strains that produce beta-lactamase enzymes.

It is used in hospitals and clinical settings for the treatment of serious bacterial infections such as pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, septicemia, and gynecological infections.

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Key Benefits:

• Broad-spectrum coverage for resistant infections

• Effective against beta-lactamase producing pathogens

• Once or twice daily dosing enhances compliance

• Rapid onset of action with IV or IM administration

• Trusted in in-patient and post-operative infection control

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How It Works:

• Ceftriaxone inhibits bacterial cell wall synthesis, leading to bacterial cell death

• Tazobactam blocks beta-lactamase enzymes that render certain antibiotics ineffective
  Together, they deliver enhanced antibacterial potency, particularly in resistant infections

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How to Use:

• Dosage and administration should be done only by a registered medical professional

• Reconstitute powder with sterile water for injection as per instructions

• Administer via IV slow injection/infusion or deep IM injection

• Frequency and dose based on severity, infection type, and patient’s renal/hepatic function

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Safety Advice:

• Monitor for allergic reactions, especially in penicillin-sensitive patients

• Common side effects may include injection site pain, mild diarrhea, or rash

• Avoid mixing with calcium-containing IV solutions

• Renal function monitoring is advised in prolonged therapy

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Precautions:

• Use only under strict medical supervision

• Not to be used in neonates with hyperbilirubinemia

• Adjust dose in patients with renal or hepatic impairment

• Discard unused solution immediately after preparation

• Store vials below 25°C; protect from light