Description
Composition (Each Tablet Contains):
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Tofacitinib (as Extended-Release) – 11 mg
Form: Oral Tablet (Extended Release)
Pack Size: 1×10 Alu-Alu
Product Description:
DOFACITI® 11 mg is a once-daily extended-release tablet of Tofacitinib, a Janus kinase (JAK) inhibitor indicated for the treatment of moderate to severe rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It works by modulating the immune system’s overactive signaling pathways responsible for inflammation and joint damage.
The extended-release formulation ensures sustained plasma levels over 24 hours, enhancing patient compliance and therapeutic efficacy with just one daily dose.
Key Benefits:
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Controls symptoms of rheumatoid and psoriatic arthritis
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Reduces joint inflammation, stiffness, and pain
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Convenient once-daily dosing
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Targeted action through JAK inhibition for improved autoimmune regulation
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May be used in patients unresponsive to conventional DMARDs
How It Works:
Tofacitinib selectively inhibits JAK1 and JAK3, enzymes involved in the signaling pathways of cytokines and growth factors. By blocking these pathways, it helps suppress abnormal immune responses that cause chronic inflammation and tissue damage in autoimmune diseases.
The extended-release matrix ensures steady medication levels throughout the day, reducing symptom flare-ups.
How to Use:
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Take one tablet once daily, preferably at the same time each day
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Swallow whole with water—do not crush or chew
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Best taken after food to minimize gastric upset
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Follow your doctor’s prescription precisely
Safety Advice:
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Regular monitoring of CBC, liver function, and lipid profile is advised
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Avoid live vaccines during treatment
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Do not consume alcohol excessively during therapy
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Inform your doctor if you develop signs of infection (fever, cough, fatigue)
Precautions:
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Not recommended during pregnancy or breastfeeding unless medically justified
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Use cautiously in patients with hepatic impairment, history of thrombosis, or chronic infections
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Avoid in patients with active tuberculosis or serious infections
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Store at room temperature, away from direct sunlight and moisture
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