Description
Composition (Each Sustained Release Tablet Contains):
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Flunarizine Dihydrochloride – 10 mg
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Propranolol Hydrochloride – 40 mg (Sustained Release)
Form: Sustained Release Tablet
Pack Size: 10×10 Alu-Alu
Product Description:
MIGRADEL® PLUS SR is a scientifically balanced migraine preventive formulation, combining Flunarizine 10mg and Propranolol 40mg SR. It is designed for patients who suffer from frequent migraine attacks, especially those with vascular or tension-type headaches. The dual-action mechanism helps reduce both the frequency and severity of migraines by regulating vascular tone and calming neuronal hyperactivity.
This sustained-release combination ensures long-lasting relief and improves patient compliance.
Key Benefits:
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Reduces the frequency, intensity, and duration of migraine episodes
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Effective in managing chronic migraine and prophylaxis of vestibular migraine
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Helps control associated symptoms like nausea, visual aura, and light sensitivity
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Improves cerebral blood flow regulation and reduces excitability of brain cells
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Once-daily sustained release dosing improves adherence
How It Works:
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Flunarizine is a calcium channel blocker that stabilizes neuronal activity, reducing the likelihood of migraine initiation.
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Propranolol is a non-selective beta-blocker that prevents migraines by lowering stress-related vascular constriction and modulating central nervous system excitability.
Together, they create a synergistic effect in preventing vascular migraine triggers.
How to Use:
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Take one tablet once daily, preferably in the evening or as prescribed
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Swallow whole with water—do not crush or chew
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Use consistently for optimal prophylactic results; not for acute migraine attacks
Safety Advice:
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May cause drowsiness or fatigue—avoid driving or operating machinery if affected
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Monitor heart rate and blood pressure regularly during treatment
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Inform your doctor if you experience mood changes, shortness of breath, or weight gain
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Avoid alcohol while on this medication
Precautions:
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Not recommended in patients with asthma, bradycardia, or depression without medical supervision
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Use with caution in elderly patients and those with a history of cardiovascular disease
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Not for use during pregnancy or lactation unless clearly indicated
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Do not abruptly stop the medication—taper gradually under physician guidance
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