NERVEDEL® – EDV Injection

Description

Composition (Per Ampoule):

• Edaravone – 1.5mg/ml

• Form: Sterile solution for intravenous administration

• Pack Size: 20ml vial

• Route of Administration: Intravenous (IV)

• Category: Neuroprotective | Free Radical Scavenger | Stroke Therapy

---

Product Description:

NERVEDEL® – EDV Injection contains Edaravone, a potent free radical scavenger used in the treatment of acute ischemic stroke and amyotrophic lateral sclerosis (ALS). It works by neutralizing oxidative stress that damages neurons during ischemic injury. Early intervention with Edaravone is shown to improve clinical outcomes and preserve neurological function in acute stroke patients.

---

Key Benefits:

• Protects brain tissue by reducing oxidative damage

• Enhances neurological recovery post-stroke

• Helps delay progression in ALS patients

• Ideal for critical care and stroke units

• Clinically proven and well-tolerated in both short-term and long-term use

---

How It Works:

Edaravone reduces damage caused by free radicals that form during ischemia and reperfusion. By inhibiting lipid peroxidation and oxidative stress, it helps protect neurons from injury and apoptosis. This action is critical in minimizing damage in acute strokes and slowing neuron degeneration in ALS.

---

How to Use:

• Administer intravenously over 30–60 minutes

• Typical stroke regimen: 30 mg twice daily for 14 days (or as advised by physician)

• Dilute in 100ml normal saline if required before infusion

• Ensure administration by trained healthcare professionals in a clinical setting

---

Safety Advice:

• Generally well tolerated; monitor for allergic reactions or liver enzyme elevation

• Monitor renal and hepatic function in long-term use

• Avoid use in patients with known hypersensitivity to Edaravone

• Not recommended for use in pregnant or lactating women unless essential

---

Precautions:

• Use with caution in patients with renal impairment or asthma

• Do not mix with other medications in the same IV line

• Store at room temperature, protected from direct sunlight

• For single-dose use only; discard unused portion