SUGAVILD® – PG Tablet

Description

Composition (Each Film-Coated Tablet Contains):

• Vildagliptin – 50 mg

• Pioglitazone Hydrochloride – 15 mg

Category: Diabetes Care / DPP-4 Inhibitor + Thiazolidinedione (TZD) Combination
Form: Oral Tablet
Pack Size: 10×10 Alu-Alu or Blister Pack

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Product Description:

SUGAVILD® – PG is a dual-action oral antidiabetic tablet combining Vildagliptin, a DPP-4 inhibitor, and Pioglitazone, a thiazolidinedione (TZD). This combination is specially designed for adult patients with type 2 diabetes mellitus (T2DM) who have insulin resistance or inadequate control on monotherapy. It addresses two key pathophysiological defects — incretin dysfunction and peripheral insulin resistance.

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Key Benefits:

• Targets both insulin resistance and beta-cell dysfunction

• Improves glycemic control in patients with poor insulin sensitivity

• Minimal risk of hypoglycemia when used without sulfonylureas or insulin

• Promotes glucose uptake in muscle and adipose tissue

• Suitable for early- to mid-stage T2DM or step-up therapy

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How it works:

• Vildagliptin inhibits DPP-4, prolonging the activity of incretin hormones (GLP-1 and GIP), which enhance insulin secretion and suppress glucagon in a glucose-dependent manner

• Pioglitazone improves peripheral insulin sensitivity by acting on PPAR-γ receptors, increasing glucose uptake in adipose and muscle tissues while reducing hepatic glucose production

Together, they offer complementary action for improving insulin response and long-term glycemic control.

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How to use:

• Take one tablet once or twice daily with meals, as directed by your physician

• Swallow whole with water — do not split or chew

• Follow prescribed diet and exercise routine for best results

• Regular blood sugar and liver function monitoring is recommended

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Safety Advice:

• May cause mild fluid retention — report swelling or rapid weight gain

• Low risk of hypoglycemia unless used with insulin or sulfonylureas

• Monitor liver enzymes periodically

• Routine eye check-up is advised during long-term Pioglitazone use

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Precautions:

• Not recommended in patients with heart failure (NYHA Class III/IV) or active liver disease

• Caution in patients with osteoporosis, bladder cancer history, or macular edema

• Avoid during pregnancy or breastfeeding

• Inform your doctor about all other antidiabetic medications or cardiac drugs

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Storage:

Store in a cool, dry place below 25°C.
Protect from light and moisture.
Keep out of reach of children.