TRIGOACT® – 40/H Tablet

TRIGOACT® – 40/H is a fixed-dose combination of Olmesartan, an angiotensin II receptor blocker (ARB), and Hydrochlorothiazide, a thiazide diuretic. This once-daily formulation provides synergistic blood pressure reduction, helping patients achieve target BP levels more effectively while offering protection against heart attack, stroke, and kidney damage in long-term hypertension management.

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Description

Composition (Each Film-Coated Tablet Contains):

  • Olmesartan Medoxomil – 40 mg

  • Hydrochlorothiazide – 12.5 mg

Category: Cardiac Care / Antihypertensive Combination
Form: Oral Tablet
Pack Size: 10×10 Blister / Alu-Alu


Product Description:

TRIGOACT® – 40/H is a fixed-dose combination of Olmesartan, an angiotensin II receptor blocker (ARB), and Hydrochlorothiazide, a thiazide diuretic. This once-daily formulation provides synergistic blood pressure reduction, helping patients achieve target BP levels more effectively while offering protection against heart attack, stroke, and kidney damage in long-term hypertension management.


Key Benefits:

  • Dual mechanism ensures better blood pressure control

  • Reduces risk of cardiovascular and renal complications

  • Helps manage resistant or uncontrolled hypertension

  • Once-daily convenience with long-lasting effect

  • Well tolerated with minimal risk of electrolyte imbalance


How it works:

  • Olmesartan blocks angiotensin II from binding to its receptors, relaxing blood vessels and lowering blood pressure.

  • Hydrochlorothiazide helps remove excess salt and fluid through urination, reducing blood volume and peripheral resistance.

Together, they complement each other by targeting different pathways in blood pressure regulation.


How to use:

  • Take one tablet daily, preferably in the morning, with or without food, or as directed by your doctor.

  • Swallow whole with water — do not crush or chew.

  • Maintain a regular schedule for consistent control.

  • Regular BP and electrolyte monitoring may be required during treatment.


Safety Advice:

  • May cause dizziness — avoid driving or operating machinery until you know how it affects you.

  • Maintain adequate fluid intake unless otherwise restricted.

  • Monitor kidney function and electrolytes (especially potassium and sodium) periodically.

  • Avoid alcohol and dehydration while on treatment.


Precautions:

  • Not suitable for patients with severe kidney disease, anuria, or hypersensitivity to sulfonamides.

  • Caution in patients with gout, diabetes, or liver disease.

  • Not recommended during pregnancy or breastfeeding.

  • Inform your doctor about other antihypertensives or NSAIDs you may be taking.


Storage:

Store in a cool, dry place, protected from moisture and direct sunlight.
Keep out of reach of children.

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