ZEMDOXY®- 200mg Injection

Description

Composition (Per Vial):

• Doxycycline Hydrochloride equivalent to Doxycycline – 200 mg
  Form: Lyophilized powder for IV reconstitution
  Route: Intravenous infusion only
  Pack Size: Single-use vial
  Category: Broad-Spectrum Antibiotic | Hospital / ICU Use | Tetracycline Class

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Product Description:

ZEMDOXY®- 200mg Injection is the higher-strength parenteral formulation of Doxycycline, designed for use in moderate to severe infections that demand potent and sustained antimicrobial action. Doxycycline is effective against a wide range of aerobic, anaerobic, atypical, and intracellular organisms, making it an ideal choice in hospital-based treatment protocols.

This formulation is especially helpful for patients who cannot tolerate oral medications and need reliable IV coverage for infections such as rickettsial diseases, pneumonia, zoonotic infections, sepsis, and post-surgical infections.

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Key Benefits:

• High-dose formulation suitable for initial loading or severe cases

• Covers Gram-positive, Gram-negative, and atypical organisms

• Effective in treating rickettsial fevers, chlamydia, malaria prophylaxis, and respiratory tract infections

• Trusted antibiotic in ICU settings

• Once or twice daily dosing due to long half-life

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How It Works:

Doxycycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, effectively stopping bacterial growth. Its bacteriostatic action covers a broad spectrum of pathogens, including Mycoplasma, Rickettsia, Borrelia, Chlamydia, and others.

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How to Use:

• Reconstitute the vial with sterile water for injection

• Administer as a slow intravenous infusion over 1–4 hours

• Dosage should be based on patient condition, weight, and renal/hepatic status

• Typically used once or twice daily under strict medical supervision

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Safety Advice:

• Avoid use in pregnant women, lactating mothers, and children under 8 years

• Monitor for signs of photosensitivity—limit sun exposure

• Use cautiously in patients with hepatic dysfunction

• Not for use in individuals allergic to tetracyclines

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Precautions:

• Do not administer as a rapid IV bolus

• Do not mix with calcium-containing IV fluids (e.g., Ringer’s Lactate)

• Reconstituted solution should be used immediately or per recommended storage instructions

• Monitor liver enzymes, renal function, and complete blood counts in prolonged use